natural alternatives to isosorbide mononitrate
We study millions of patients and 5,000 more each day. Yet many herbal supplements may interact with heart disease medicines. eCollection 2021. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. AHFS Patient Medication Information. The Swedish Multicentre Group. If you become pregnant while taking isosorbide, call your doctor. Almost 70% of older adults use them. https://naturalmedicines.therapeuticresearch.com. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. It has a very short duration of action and may not be suitable for some people. Talk to your doctor if you are using marijuana (cannabis). Seek alternatives to the CYP3A4 substrate when possible. It can cause your blood pressure to become dangerously low. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. MeSH In: Current Medical Diagnosis & Treatment 2022. The herb licorice may lower warfarin levels and can add to digoxin's effects. You need to take it every day in order for it to work. Do not store in the bathroom. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). Even if the medication is working, you may experience some unwanted side effects. Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. Click here for an email preview. Call your doctor if you have any unusual problems while you are taking this medication. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Does isosorbide mononitrate (Monoket) affect your kidneys? You can develop a tolerance to isosorbide mononitrate (Monoket) over time, which means the dose you've been taking doesn't work as well. Anti-ischemic and anti-anginal effects of controlled-release and conventional isosorbide-5-mononitrate in stable angina pectoris. Otherwise, call a poison control center right away. isosorbide mononitrate, along with Isosorbide mononitrate: isosorbide mononitrate. Never give it to other people even if their condition appears to be the same as yours. Talk to your provider if you continue to feel dizzy or have a fast heart rate a week after starting isosorbide mononitrate (Monoket). Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. Accessed Sept. 7, 2022. Avoid combinations; the risk of the interaction outweighs the benefit. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Dehydration in Buspar, how severe and when it was recovered? Accessed Sept. 7, 2022. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. It is best not to drink alcohol while you are on isosorbide mononitrate. Be sure to mention any of the following: aspirin; beta blockers such as atenolol (Tenormin, Tenoretic), carteolol , labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, in Dutoprol, in Lopressor HCT), nadolol (Corgard, in Corzide), propranolol (Hemangeol, Inderal, Innopran), sotalol (Betapace, Sorine, Sotylize), and timolol; calcium channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), diltiazem (Cardizem, Cartia, Dilt-CD, others), felodipine (Plendil), isradipine, nifedipine (Adalat CC, Afeditab, Procardia), and verapamil (Calan, Covera, Verelan); ergot-type medications such as bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. 1996 Dec;3(12):802-806. doi: 10.1097/00045391-199612000-00003. Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. from the best health experts in the business. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. If you have any questions about this medicine ask your pharmacist. Are you looking for information on isosorbide dinitrate (Isordil) instead? Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. Continue to take isosorbide even if you feel well. May also be prescribed off label for Esophageal Spasm. Unless there is a specific reason you need the brand, the generic medication will be a better value. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. In: Textbook of Natural Medicine. Eur Heart J. PMC Copyright, 2023. What should I know about storage and disposal of this medication? URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. US residents can call their local poison control center at 1-800-222-1222. May also be prescribed off label for Esophageal Spasm. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. To use the sharing features on this page, please enable JavaScript. Registered in England and Wales. A very serious allergic reaction to this drug is rare. Which drugs or supplements interact with isosorbide mononitrate? Review/update the Tell your doctor right away if you have any serious side effects, including: fainting, fast/irregular/pounding heartbeat. Liperoti R, et al. Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. Natural Medicines. You can consult me online for homeopathic treatment. Minimally clinically significant. I strongly feel that there is coronary ischemia. The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. Accessed Sept. 7, 2022. information is beneficial, we may combine your email and website usage information with Keep this medication in the container it came in, tightly closed, and out of reach of children. If you have an underactive thyroid gland. All rights reserved. include protected health information. What are the interactions of Isosorbide Mononitrate ? Federal government websites often end in .gov or .mil. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? It works to relax your blood vessels. B complex. Some products that may interact with this drug include: drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), riociguat. Now, youll enjoy a streamlined experience created specifically for healthcare providers. If you have an eye condition called glaucoma. Some don't work well with prescription medicines. This is so your doctor can check on your progress. Pricing based on most commonly-filled versions: 180 tablets of isosorbide mononitrate 10mg. The most common side-effect is headache. ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. This medicine is available only with your doctor's . It does not work fast enough to relieve the pain of an angina attack that has already started. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Treatment and prognosis of heart failure with preserved ejection . The authors assessed the occurrence of angina pectoris and headache by diary cards while taking into account the number of isosorbide dinitrate sublingual puffs and paracetamole tablets required. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. 2017; doi:10.1016/j.jacc.2016.11.078. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. [2] Portions of this document last updated: Feb. 01, 2023. Your doctor will prescribe you a short-acting nitrate for you to take if this happens. Accessed Sept. 7, 2022. Normal ecg doesn't rule out heart disease. Watch for any symptoms that you may be having a drug interaction, such as: Mayo Clinic does not endorse companies or products. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). The two dosage regimens were equally efficient for the relief of angina pectoris without development of tolerance. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Isosorbide Mononitrate side effects by likelihood and severity. Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. Along with its needed effects, a medicine may cause some unwanted effects. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Sildenafil ( Viagra ), tadalafil ( Cialis ), avanafil ( Stendra ),and vardenafil ( Levitra) increase the blood pressure lowering effects of isosorbide mononitrate and may cause excessive reductions in blood pressure. Things to remember when you fill your prescription. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. Nitroglycerin works very quickly to widen your blood vessels and help your heart pump blood during a heart attack. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Please upgrade your browser or download modern browsers from here! May also be prescribed off label for Esophageal Spasm. These products are provided 'AS IS' and 'as available' for use, without warranties of any kind, either express or implied. Dated August 2017. No, that's not true all the time. https://naturalmedicines.therapeuticresearch.com. This site needs JavaScript to work properly. Talk to your pharmacist for more details. Unauthorized use of these marks is strictly prohibited. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. This medication belongs to a class of drugs known as. Isosorbide mononitrate is a nitrate-class drug used for the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. 2005 - 2023 WebMD LLC. Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. View more, Nitroglycerin dilates veins, relieving chest pain and lowering blood pressure. 46 ratings on Drugs.com. Store it at room temperature and away from excess heat and moisture (not in the bathroom). privacy practices. Do not stop taking isosorbide without talking to your doctor. Use this medication regularly to get the most benefit from it. Isosorbide mononitrate. Lyrica and Metoclopramide drug interaction, Calcitriol and Metoclopramide drug interaction. The extended-release tablet usually is taken once daily in the morning. Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). B12 and folic acid is essential along with iron. I took this for 4 days, and my headaches were unbearable. Some products have ingredients that could worsen your heart failure. There are no data on passage of isosorbide mononitrate in human milk, but some excretion seems likely. Prescribed for Angina, Anal Fissure and Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. Elsevier; 2021. https://www.clinicalkey.com. Take isosorbide exactly as directed. Read our editorial policy. Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. If you notice other effects not listed above, contact your doctor or pharmacist. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. This makes it easier for your heart to pump, relieving heart-related chest pain. St. John's wort. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Isosorbide mononitrate helps to prevent angina chest pain from developing. Accessed Sept. 7, 2022. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. What You Need to Know, Angina (a specific type of chest pain) caused by heart disease. Prescription and OTC Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. Isosorbide mononitrate (Monoket) is available as both a immediate-release (IR, short-acting) and extended-release (ER, long-acting) tablet. Journals of the American College of Cardiology. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. 41% of reviewers reported a positive effect, while 50% reported a negative effect. Selected from data included with permission and copyrighted by First Databank, Inc. Do not stop taking it without consulting your doctor. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Natural Medicines. Overview of herbal medicines and dietary supplements. 67% of reviewers reported a positive effect, while 13% reported a negative effect. Accessibility The narrowing makes it more difficult for blood to flow to your heart muscle. Natural Medicines. Always consult your healthcare provider. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. Mayo Clinic does not endorse companies or products. Natural Medicines. These relax smooth muscle within the blood vessels, widening them and making it easier for blood and oxygen to reach the heart Calcium antagonists (eg, diltiazem, nifedipine, nimodipine, verapamil). The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Browse Drugs and Medicines. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. Using this medicine with any of the following medicines is not recommended. Your doctor will schedule your doses so that there is a period of time every day when you are not exposed to isosorbide. You may report side effects to the FDA at 1-800-FDA-1088. Longer-acting tablets and capsules are taken once daily in the morning. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. Some of these medicine interactions can be risky. Valerian: A safe and effective herbal sleep aid? Medicines containing Isosorbide Mononitrate. It is important that you follow the instructions your doctor gives to you about when to take your doses. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. A single copy of these materials may be reprinted for noncommercial personal use only. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. If this worries you, talk to your doctor or pharmacist about other options. Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. Isosorbide mononitrate helps to prevent angina chest pain from developing. Clin Res Cardiol. It does not have such side effects. St. Joseph 81 mg Aspirin Enteric Safety-Coated. The list below does not include all possible drug interactions with isosorbide mononitrate (Monoket). It is important to take the drug at the same times each day. As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. information and will only use or disclose that information as set forth in our notice of Limit alcoholic beverages. See the full pregnancy warnings document. Select a condition to view a list of medication options. Isosorbide dinitrate (Isordil) is available as both a short-acting tablet and long-acting capsule. The extended-release tablet usually is taken once daily in the morning. Elantan, Imdur, Isotard, Monomax, Tardisc, Xismox. Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. Do not share this medication with others. 72% of reviewers reported a positive effect, while 12% reported a negative effect. Isosorbide mononitrate (Monoket) works slowly to help prevent chest pain. It can make you really dizzy. What side effects can this medication cause? Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. Call your doctor for medical advice about side effects. Then, there was a two-week placebo washout, after which the alternative treatment was given. What special precautions should I follow? The use of the Truven Health products is at your sole risk. Although not all of these side effects may occur, if they do occur they may need medical attention. Do not take more or less of it or take it more often than prescribed by your doctor. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. Severe postural hypotension with light-headedness and dizziness is frequently observed after the consumption of alcohol. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. daily and increasing to 40 mg three times daily as necessary, given at 8 AM, 1 PM, and 6 PM), isosorbide mononitrate (starting at 30 mg/day in the morning and increasing to 120 mg/day as necessary), or a transdermal. Get emergency help immediately if any of the following symptoms of overdose occur: bulging soft spot on the head of an infant, change in the ability to see colors, especially blue or yellow, feeling of constant movement of self or surroundings. (1) Starting on a low dosage was associated with a reduced frequency and severity of headache and did not notably influence the beneficial effect on angina pectoris. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. It might help to keep the room cool and use a fan. Take the missed dose as soon as you remember it. However, you should not flush this medication down the toilet. Duplication for commercial use must be authorized by ASHP. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. Canada residents can call a provincial poison control center. Tachjian A, et al. If you have any problems with the way your liver works, or any problems with the way your kidneys work. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Many herbal supplements can interact with prescription drugs. This is called a medicine interaction. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Is not subject to the Controlled Substances Act. Isosorbide mononitrate (Monoket) is good for a specific type of chest pain (called angina), but it can cause headaches or dizziness after you take it. https://naturalmedicines.therapeuticresearch.com. If you forget to take a dose, take it as soon as you remember. Do not take a double dose to make up for a missed one. 2010; doi:10.1016/j.jacc.2009.07.074. In the US - Call your doctor for medical advice about side effects. Isosorbide mononitrate is very similar to isosorbide dinitrate. Changing positions slowly can help lessen dizziness. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. Contact your provider right away if you feel as if you are going to pass out and are experiencing an irregular heartbeat, nausea, vomiting, changes in vision, more sweating, or cold and clammy skin. Usually avoid combinations; use it only under special circumstances. Highly clinically significant. the unsubscribe link in the e-mail. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. A randomized, double-blind, cross-over study. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. Never take more than the prescribed dose. 55 ratings on Drugs.com. Natural Medicines. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.